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14 patients,aged 2-28 years,with neuromuscular disorders and symptomatic sleep hypoventilation received night-time intermittent positive-pressure ventilation with a nasal mask.9 were treated de nuvo and 5 had previously been maintained on a cuirass or iron lung.Nasal ventilation was very effective in 10 patients but was not tolerated in 4 of the 5 youngest patients.Nasal ventilation was preferable to other methods of ventilation because the system was noninvasive,quiet,portable,and easy to use and because it allowed considerable independence. |
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